RTP Segmentation - exclude ISP or no?

[JD_Nelson]

I created a segment for our target ABM industries; for this example, we'll use "Financial Services"

When I create the segment, should I exclude ISPs as a secondary filter? My thought is that someone could be identified as Financial Services, but then possibly work from home or a coffee shop (on an ISP) and then be dq'd from my campaign? ...or maybe I don't fully understand how it works.

Input? Thoughts?         

[Josh_Hill13]

Excluding ISPs will prevent people identified by generic comcast.net locations. It will never be perfect. Most people exclude it.

[JD_Nelson]

but what's the overriding factor -- I want to look at industry primarily and IF none, then exclude ISP; but if industry happens to be known, and they're at an ISP location, then that's fine.