SOLVED
Hi Amanda,
I read through this thread and thought it required an answer that brings everything together. 
In the responsive design era what you are wanting to do has become more complicated than before. In the classic design era (4+ years ago 
) you could use what are called image maps which is HTML that basically puts a grid on top of your image so the browser can be told there are certain hotspots on an image. Another option was to slice up the image and put it back together using tables so that you could isolate a piece of the image to put a link on.
Neither of those options work in responsive design though because your image scales and adjusts to the size of the browser window making it impossible to use those two techniques for obvious reasons. There are new solutions though, like using jQuery or SVG, but both require extensive coding experience.
Google has made it clear that your Web pages (landing pages) must be designed using responsive design techniques or your Web site will be left behind so if you need to do an image like map within Marketo you will have to be able to do the coding required to use jQuery or SVG. Email on the other hand is another matter. I think it is safe to use classic design techniques in email still, provided you use images sparingly and text on images sparingly. If our clients require us to use image maps we will use classic email design, however, even in that case you still have to be comfortable enough with coding to be able to create and insert the HTML into the email. Dreamweaver is the simplest way to create a map and you can add that code directly into the mktEditable locations in the email.
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