The URL for API version 2.1 can be found at Admin - SOAP API
It is displayed as "SOAP endpoint".
In the past the endpoint was generic for a cluster.
The Munchkin ID, unique for each instance, has been added to recent releases.
That is an important security enhancement.
The endpoint for a theorethical Munchkin ID ABC-123-000 would be
https://ABC-123-000.mktoapi.com/soap/mktows/2_1
The WSDL can be found at
https://ABC-123-000.mktoapi.com/soap/mktows/2_1?WSDL
Please kee in mind the Munchkin ID is distinct for each instance no matter it is sandbox or production.