Hello Stephen,
Yes, you can use my.tokens or lead. tokens in the From Email, From Name, Reply-To and Subject line places. However, if you use tokens in the subject line, it makes the sales team unable to fully see the email Subject Line in Sales Insight for SFDC since tokens are not rendered through to the plugin. This is a more advanced feature and lives in SFDC and may not be an issue at this time depending on your use of Sales Insight.
Hope that helps!
Ericka