Please see this thread:
Marketo Removing Code for Image Scaling for Outlook at 125%dpi
We have resolved this issue and can enable the fix for your subscription if you're interested. Please see the comments in the idea above for more details.
I just finished testing... AND IT WORKS!!!! Thanks so much, Justin! BTW, it's not just the DOCTYPE that caused the issues, but Marketo was also stripping the xmlns definitions within the <HTML> tag, just after the DOCTYPE. These critical three lines of code are now also being preserved.
Other related discussions can be found here:
Marketo Removing Code for Image Scaling for Outlook at 125%dpi
It would be great to do things like background images: http://backgrounds.cm/ or styled buttons: http://buttons.cm/ or hide mobile content in responsive emails in outlook: http://freshinbox.com/blog/bulletproof-solution-to-hiding-mobile-content-when-opened-in-non-mobile-email-clients/
It all requires MSO conditional statments. Outlook uses a Word rendering engine... it needs to be individually targeted.