I would like to hear your experiences when you have built a preference center based on topics of interests.
There are dozens of threads on this.
Building a Full Subscription Center in Marketo -Marketing Rockstar Guides
Subscription Management Center -Marketing Rockstar Guides
Email Subscription Center - Marketo
There's one or two here too: Marketo Whisperer: Implementation Tips
Define your version of "simple" though It is mostly about planning.