Hi Jason,
Yes, absolutely. You don't have to clone the asset to do so either, but if you keep it in one "Content" channel program, you won't get any Success metrics on your other channels... Email, Online Advertising, etc. It will result in multiple programs getting credit for Success for the same asset, but you can analyze First Touch and Multi Touch attribution to distinguish.
If you do not use multiple Programs to reflect every channel, your Program Analyzer will be less useful since it won't show you the ROI of each Channel compared to others.
Hope that helps!