It IS possible to implement bootstrap. I haven't personally done it, but I have implemented Foundations, which is a similar responsive framework.
That being said, I implemented it in a way that I am not making use of the landing page editor anymore. Basically, my template loads up the framework and then I just drop an HTML item on the actual page and put everything else in there. There's several drawbacks to this method, but I prefer it since it gives me more flexibility than the alternative.
There's ways to make responsive templates and still use the WYSIWYG editor, but I find it's more trouble than it's worth.