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Hi David
As others have mentioned, there is no way to do this within Marketo - and I haven't seen it in other marketing automation software either. I love that you are into the subject since A/B testing is one thing, A/B testing with proper science behind it is completely another.
One thing Marketo lacks that is much simpler to implement is a p value calculator for the results. We always see "A is the winner since it had 1100 opens, while B only had 1050 opens". But in reality, as you probably know, that result might be completely meaningless if the sample size wasn't large enough, and might be purely random variation.
Here's a calculator I use to determine whether my results are statistically significant after the test is run: A/B Test Calculator: MeasuringU
Estimating the sample size, as Rhianne Makovec mentioned, can be done with online calculators. But - this requires estimating the proportions ahead of time, which is a bit of educated guesswork. So it's always worthwhile analysing the results for statistical significance after the fact to make sure the effect you see is likely the result of the test.
Phil