How early/late stage is your trial? Is it a primary lead source for you, or late stage that strongly indicates a likelihood to buy?
I've seen this done a few different ways, but thinking back to the customers I've spoken with these are the common approaches:
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When someone fills out a free trial, make a lead in SFDC unless trials are very early stage indicators of interest and you'd have too many inbound leads
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I'd track all signups as an "Interesting Moment" which you'd see under the lead, but not create multiple leads
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Depending on how you want to report in SFDC, just using Interesting Moments may not be enough, you may want to try and have some other object be created in SFDC by whatever automates your trial provisioning
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Generally the answer on creating opportunities gets back to the early/late stage behavior question. If it is early interest, don't. If it is late stage, do it.
-Erik