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There is no benefit in doing so, IMHO.
The 3 notions are separate and should reflect different situations.
All of them are excluded from communications anyway (although email invalid and blacklisted are even excluded from operational emails, while unsubscribed are not).
All of them are excluded from the marketale database count.
Black listed are for people you really want to excluded, even if they are not unsubcribed not hard bounced.
If you want a count of your addressable database, just create a smart list that combines the 3 criteria.