We hare considering RTP not to replace but to add some content to an existing page.
In, order to do this, we would add a blank div to a page, at the specific location, but this div would be empty an height 1px.
Then we would define the in zone campaign to add some content to this zone for specific segments, the idea being that the content defined in the campaign would obviously be higher than 1 pixel and that the page would automatically expand in size (it has been designed for this).
Yes it can. Recommended to test and preview it before launching.