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Josh, this is how we do it:
We setup our nested programs within the main program and setup trigger campaigns in each to deal with Opens and Clicks, then in each Email Send we see stats as follows under the Summary View:
For syncing, we have another trigger campaign in each program and when people meet the criteria, they then get sync'd.
One thing to remember when using the nested structure above, that only trigger campaigns should be used in the Email Send Program, using batch campaigns within it messes up the easy dashboard in the Email Send and goes against why you use an Email Send. This isn't documented well anywhere but you'll notice issues when trying to do quick reporting.
You can then to A/B testing within each program or use Random Sample to create a Static List and use that in the Smart List to do a manual A/B test.