3 of 3 people found this helpful
Unfortunately Out of Offices, etc are set on the email client side and each client decides on whether to use the Reply or From to address for replies.
1 of 1 people found this helpful
+1! Usually automated replies go to the from, and human responses go to the reply-to. This is helpful if you don't want to get inundated with out of office responses.
Unfortunately this is an equation with many variables. See these two articles that give an explanation of how this works in detail.
See the answer with 5 votes.