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You could use a trigger smart campaign based on the the data value change of lead status with a new value of MQL. The flow would be to wait two days. Then send an alert, but add a choice for lead status is equal to MQL. If someone is still an MQL, then you can send them the defined alert. The default choice would be to do nothing. Anyone who is no long an MQL lead status would result in the do nothing choice.
this is the basic setup for an SLA system. Keep in mind that there are more complex methods, but this is the one you want right now.