A binding e-signature would need to be generated by a service like SignNow, HelloSign, etc. You can store a pointer to the e-signature in Marketo and it’ll sync to your CRM.
This will work fine as long as you don’t lose the e-signature field — that is, as long as it’s filled in, you can present it as evidence that the form (“document” more broadly) was signed. If you should delete the e-signature... well, that’ll create a problem on your side, but it’s incumbent upon you to not delete it!
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